Search results for "Nerve manipulation"

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Development and external validation of a clinical prediction model for functional impairment after intracranial tumor surgery

2021

OBJECTIVE Decision-making for intracranial tumor surgery requires balancing the oncological benefit against the risk for resection-related impairment. Risk estimates are commonly based on subjective experience and generalized numbers from the literature, but even experienced surgeons overestimate functional outcome after surgery. Today, there is no reliable and objective way to preoperatively predict an individual patient’s risk of experiencing any functional impairment. METHODS The authors developed a prediction model for functional impairment at 3 to 6 months after microsurgical resection, defined as a decrease in Karnofsky Performance Status of ≥ 10 points. Two prospective registries in…

AdultMaleMicrosurgerymedicine.medical_specialtyFunctional impairmentAdolescentIntracranial tumorNerve manipulationoutcome predictionYoung Adult03 medical and health sciencesPostoperative Complications0302 clinical medicinePredictive Value of TestsHumansMedicineGeneralizability theoryneurosurgeryProspective StudiesRegistriesKarnofsky Performance StatusAgedRetrospective StudiesAged 80 and overBrain Neoplasmsbusiness.industryExternal validationArea under the curveReproducibility of ResultsGeneral MedicineMiddle AgedSurgerypredictive analyticsmachine learningfunctional impairment030220 oncology & carcinogenesisoncologyCohortFemaleNeurosurgerybusiness030217 neurology & neurosurgeryJournal of Neurosurgery
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